PGT-M requires the creation of a specific probe or “barcode” to test the embryos for the specific pathogenic variant(s) linked to the disorder of concern while also cataloging specific genetic markers (called single-nucleotide polymorphisms) around the pathogenic variant(s) to maximize the accuracy of the testing. This is performed for both reproductive partners.
Each PGT-M test is tailor-made for each individual family, using the “barcodes” from each family identified from DNA samples (usually provided via cheek swab) from both partners and frequently additional family members.
The fertility clinic will review the results from the genetic testing company with you. Embryos will be identified that are suitable for transfer and do not contain the genetic variant(s) of concern. At that time, your provider will address any other issues related to the embryos
